Introduction to mathematical oncology

You can find material on a graduate course for introduction to mathematical and computational oncology.
  • The slides of the course that cover an introduction to cancer biology and clinical oncology basic concepts and historical use of mathematical methods to: 1) better understand tumor growth and metastatic dynamics laws and 2) better predict tumor growth, metastatic state and the effect of therapeutic interventions.
  • A "hands-on" session devoted to modeling experimental data of tumor growth. It covers in part the contents of the publication Classical Mathematical Models for Description and Forecast of Preclinical Tumor Growth. Please cite this paper when using this material.
  • Parameter estimation

    You can find here a short introductive course to statistical parameter estimation (in french).

    Population pharmacokinetics modeling using Monolix

    You can find here the text of a practical hands-on session on parameter estimation using the excellent software Monolix. It deals with the modeling analysis (within the mixed-effects statistical framework) of pharmacokinetics data of warfarin. See also the warfarin case study video by the Lixoft team, which inspired part of this material. (NB: a Monolix license is required. Monolix is free for academic researchers/students).